Cetirizine Hydrochloride

Pharmacokinetic parameters of cetyrizine at its intake in doses from 5 to 60 mg change linearly. Suction Tmax in plasma is (1±0.5) h, and Cmax is 300 ng/ml. Pharmacokinetic parameters such as Cmax in plasma and AUC are homogeneous. Food intake does not affect the completeness of cetyrizine absorption, although its rate is decreasing. The …